The concept of designing new drug therapies and new drug development programs will meet great revolutions very soon. Bugs in human gut will be future way to tackle with the several of the diseases, according to a ‘Perspective’ writing published in the journal “Nature”.

Human gut normally symbiotically imbibes trillions of bugs, scientifically called as the ‘gut microbes’. These ‘gut microbes’ have a key role to play in the human body processes. Nature of these ‘gut microbes’ will be different in every individual. Scientists have been successful in establishing a direct linkage between any abnormality in the ‘gut microbes’ and the diseases like diabetes and obesity.

Drug therapies presently have a focus revolving around the human body mechanisms. Most of the drug development programs are also having the same focus across the world. ‘Perspective’ writers are of view that the focus must shift now towards targeting the ‘gut microbes’. Such a renewed strategy would help in arrive at increased possibility level for devising new drug therapies and for fighting several diseases. However, the scientists also impress upon further research in order to explore the role played by different types of bugs in human body.

The knowledge of influence of bugs on the human body is a very recent phenomenon. Scientists are very much optimistic about the future of drug development programs. With the re-engineering of human cells and using the specified signaled pathways inside the human body, it would be far easier to create new drugs that will produce different results with induced changes in the bugs.” If we’re not interfering with the body’s pathways, these drugs should have less toxic side-effects”, hopes Professor Jeremy Nicholson, a lead ‘Perspective’ writer at the Department of Bimolecular Medicine, Imperial College London.

‘Gut microbes’ are lot dependent on the diet and other environmental factors. Therefore, an individual will have different set up of ‘gut microbes’ that will be uncommon with other individuals. Scientists at the ‘Imperial College London’ have recently demonstrated with the study results that such a typical individual set up and makeup of the ‘gut microbes’ can be changed. This change and alteration is possible through the process of making changes in the metabolic probiotics.

It becomes very clear that by introducing changes in the diet can easily change the basic characteristics of the ‘gut microbes’ in any individual. This hypothesis opens up doors for future developments of new drug therapies. Such a major shift will also facilitate new holistic approaches to the world of medicines. It will be a paradigm shift from the pharmaceutical treatments to the lifestyle and nutrition based treatments.

Scientists feel that in coming ten years or so, they will be creating new medicines and designing new drug therapies with these bugs’ orientations.