On Tuesday a research study published in Cell Metabolism, March issue, found that in obese mice, blocking the signal in fat tissue prevents insulin resistance. This new research was conducted at the Salk Institute for Biological Studies by Marc Montminy and his team.
Researchers told that a signal known for playing while fasting becomes active in the fat tissue of obese mice, while type2 diabetes is in the early stages of progression. It had been found in previous researches that blood sugar levels are kept in balance by CREB pathway during fasting. However, heightened CREB activity in diabetes triggers higher sugar levels.
In the current research, it was aimed to find whether in mature fat tissues CREB was significant or not. The researchers found that in fat cells of obese mice, by lowering the production of a hormone known as adiponectin and insulin sensitive glucose transporter; GLUT4, CREB activity supports insulin resistance.
Read the rest of this entry
UK’s top researchers in an article say that access restriction to patient record data for the researchers will hurdle patient care. This article has been published in the journal ‘Pulse’ and it shows the suspicion that concealment of patients’ data will lead to distances between clinical trials treatments and patients.
An important assurance has been averted by the UK government allowing researchers to access identifiable patients’ record; a right in the NHS constitution. According to it, patient consent was not required to do the needful.
Whereas, researchers say it is an indispensable requirement to be able to access patient data without having to seek consent first. According to director of the Wellcome Trust, Sir Mark Walport, the NHS Constitution was acting rightly but the government has acted nervously over the access to patient records.
Read the rest of this entry